Alan Bateson

Dr. Bateson joined Ross in September 2011 as a Professor of Pharmacology and was appointed Iterim Chair in 2014. His PhD was awarded in 1987 from the University of London (King’s College), UK, in biochemistry and molecular biology. From 1988 to 1992 he worked on the molecular neurobiology of GABA-A receptors as an MRC post-doctoral fellow at the Molecular Neurobiology Unit, Medical Research Council Centre, Cambridge, UK. Dr. Bateson took up his first faculty position in 1992 in the Department of Pharmacology, University of Alberta, Canada, with adjunct appointments in Psychiatry and Neuroscience. He established his research on the mechanisms underlying benzodiazepine tolerance and the regulation of expression of GABA-A receptor genes. He also taught undergraduate science and medical students as well as graduate students. In 2001, Dr. Bateson returned to the UK taking up a position in the Faculty of Biological Sciences, University of Leeds, where he continued his research and teaching activities. He was Leader for degree programmes in Pharmacology as well as participating in a number of strategic initiatives to develop the curriculum and increase teaching efficiency while maintaining an excellent student experience.

Through his career Dr. Bateson has received funding for his research from a number of agencies including MRC Canada, CIHR, AHFMR, the Royal Society, the Wellcome Trust and the BBSRC. He served as an elected member on the councils of both the Canadian College of Neuropsychopharmacology and the British Association for Psychopharmacology and was Meetings Secretary for the British Association for Psychopharmacology. He was a member, and then Chair, of the CIHR Pharmacology and Toxicology Committee, and was a member, and is currently Chair of the CIHR Vanier Canada Graduate Scholarships Peer Review Committee. He has published numerous peer-reviewed papers as well as reviews and book chapters, primarily in the area of GABA-A receptor neuropharmacology, but also on other ion channels important in cardiovascular function.

Selected Publications:

Baldwin, D.S., Aitchison, K., Bateson, A., Curran, H.V., Davies, S., Leonard, B., Nutt, D.J., Stephens, D.N. and Wilson, S. Benzodiazepines: Risks and benefits. A reconsideration. (2013) J. Psychoparm., 27, 967-971.

Dedman, A.M., Majeed, Y., Tumova, S., Zeng, F., Kumar, B., Munsch, C., Bateson, A.N., Wittman, J., Jäck, H.M., Porter, K.E. and Beech, D.J. (2011). TRPC1 transcript variants, inefficient nonsense-mediated decay and low up-frameshift-1 in vascular smooth muscle cells. BMC Mol. Biol., 12, 30.

Bateson, A.N. (2010) Pharmacology of the GABA-A receptor complex. In: Insomnia: Diagnosis and Treatment. (Sateia, M.J. and Buysse, D.J. eds.), Informa Healthcare, Inc., New York, pp. 365-374.

Wilson, S.J., Nutt, D.J., Alford, C., Argyropoulos, S.V., Baldwin, D.S., Bateson, A.N., Britton, T.C., Crowe, C., Dijk, D.J., Espie, C.A., Gringras, P., Hajak, G., Idzikowski, C., Krystal, A.D., Nash, J.R., Selsick, H., Sharpley, A.L. and Wade, A.G. (2010) British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders. J. Psychopharmacol., 24, 1577-1601.

Bahnasi, Y.M., Wright, H.M., Milligan, C.J., Dedman, A.M., Zeng, F., Hopkins, P.M., Bateson, A.N. and Beech, D.J. (2008) Modulation of TRPC5 cation channels by halothane, chloroform and propofol. Br. J. Pharmacol., 153, 1505-1512.

Xu, S.-Z., Muraki, K., Zeng, F., Li, J., Sukumar, P., Shah, S., Dedman, A.M., Flemming, P.K., McHugh, D., Naylor, J., Cheong, A., Bateson, A.N., Munsch, C.M., Porter, K.E. and Beech, D.J. (2006) A sphingosine-1–phosphate-activated calcium channel controlling vascular smooth muscle cell motility. Circ. Res., 98, 1381-1389.

Flemming, P.K., Dedman, A.M., Xu, S.Z., Li, J., Zeng, F., Naylor, J., Benham, C.D., Bateson, A.N., Muraki, K. and Beech, D.J. (2006) Sensing of lysophospholipids by TRPC5 calcium channel. J. Biol. Chem. 281, 4977-4982.

Hilton, K.J., Bateson, A.N. and King, A.E. (2006) Neurotrophin-induced preprotachykinin-A promoter modulation in organotypic rat spinal cord culture. J. Neurochem., 98, 690-699.

Hartness, M.E., Brazier, S.P., Peers, C., Bateson, A.N., Ashford, M.L. and Kemp, P.J. (2003) Post-transcriptional control of human maxiK potassium channel activity and acute oxygen sensitivity by chronic hypoxia. J. Biol. Chem., 278, 51422-51432.

Bateson, A.N. (2002) Basic pharmacologic mechanisms involved in benzodiazepine tolerance and withdrawal. Curr. Pharmaceut. Des., 8, 5-21.