Dr. Steen Pedersen joined Ross University in the spring of 2017. Prior to that he had 27 years as a faculty member at Baylor College of Medicine’s Department of Molecular Physiology and Biophysics. The main focus of his efforts there were running a lab dedicated to applying biophysical techniques, such as fluorescence and stopped-flow kinetics to understanding the mechanism of ion channels. His lab was supported by federal and private funding for more than twenty years.
Over the course of his tenure at Baylor, Dr. Pedersen taught various courses in cell biology, biochemistry, ion Channels, and grant writing skills to graduate students. In addition, he taught metabolism in the medical school to first year medical students for several years. In addition he participated actively in faculty educational development, including serving on the Fullbright and Jaworski Award review panel and chairing the Educational Research committee.
Upon joining Ross University, Dr. Pedersen has been involved in teaching in the biochemistry component of the basic science curriculum, focusing on metabolism.
1975 – 1977 California Institute of Technology Chemistry
1977 – 1979 University of Maryland College Park Chemistry BS
1979 –1984 University of Virginia Biochemistry PhD
Dissertation: Reconstitution of β-Receptors.
Advisor: Elliott M. Ross.
1984 – 1989 Washington University School of Medicine.
Advisor: Jonathan B. Cohen; supported by NIH fellowship, 1984 – 1986.
B.S. with Honors, University of Maryland
National Institute of Health Postdoctoral Fellowship.
NIH Research Career Development Award.
8-Stranded -Barrel Jelly Roll Award for Teaching Excellence
8-Stranded -Barrel Jelly Roll Award for Best Course
Fullbright and Jaworski Faculty Excellence Award in Education
Marc Dresden Award for Excellence in Graduate Education
Barbara and Corbin J. Robertson, Jr. Presidential Award for Excellence in Education
8-Stranded -Barrel Jelly Roll Award, Best Lecturer
Society of General Physiologists
American Society for Biochemistry and Molecular Biology
American Chemical Society
American Association for the Advancement of Science
Selected Peer-Reviewed Publications:
Andreeva, I. E., Nirthanan, S., Cohen, J. B., and Pedersen, S. E. Site Specificity of Agonist-Induced Opening and Desensitization of the Torpedo californica Nicotinic Acetylcholine Receptor. Biochemistry, 45, 195-204, 2006. (PMID: 16388595)
Meltzer, R.H., Thompson, E., Soman, K.V., Song, X.-Z., Ebalunode, J.O., Wensel, T.G., Briggs, J., and Pedersen, S.E. Electrostatic Steering at Acetylcholine Binding Sites. Biophysical Journal 91, 1302-1314, 2006. (PMCID: PMC1518644)*
Meltzer, R.H., Lurtz, M.M., Wensel, T.G., and Pedersen, S.E. Determination of Pore Electrostatics in the Nicotinic Acetylcholine Receptor by Diffusion-Enhanced Luminescence Energy Transfer. Biophysical Journal 91, 1315-1324, 2006. (PMCID: PMC1518635)*
Meltzer, R.H., Vila-Carriles, W., Ebalunode, J.O., Briggs, J., and Pedersen, S.E. Computed Pore Potentials of the Nicotinic Acetylcholine Receptor. Biophysical Journal 91, 1325-1335, 2006. (PMCID: PMC1518625)
Shlyonsky, V.G., Markin, V.S., Andreeva, I.E., Pedersen, S.E., Simon, S.A., Benos, D.J. and Ismailov, I.I. Role of membrane curvature in mechanoelectrical transduction: Ion carriers nonactin and valinomycin sense changes in integral bending energy. Biochimica et Biophysica Acta 1758, 1723-1731, 2006. (PMID: 17069752)
Zhang, X., Andrews, J.N. and Pedersen, S.E. Kinetic Modeling and Fitting Software for Inter-connected Reaction Schemes: VisKin. Analytical Biochemistry 361, 153-161, 2007. ( PMCID: PMC2048535)
Halling, D.B. Georgiou, D.K. Black, D. J. Yang1, G., Fallon, J.L., Quiocho, F.A., Pedersen, S.E., and Hamilton, S.L. Determinants in CaV1 Channels that Regulate the Ca2+ Sensitivity of Bound Calmodulin. Journal of Biological Chemistry, 284: 20041 - 20051 ,2009. (PMCID: PMC2740430)
Mallipeddi, P.L. Pedersen, S.E., Briggs, J.M. Interactions of acetylcholine binding site residues contributing to nicotinic acetylcholine receptor gating: Role of residues Y93, Y190, K145 and D200. Journal of Molecular Graphics and Modelling, 44, pp. 145-54, 2013 (PMID: 23831994).
Blesson, C.S., Schutt, A.K., Balakrishnan, M.P. Robia G. Pautler, R.G., Pedersen, S.E., Sarkar, P., Gonzales, D, g, Zhu, G., Marini, J.C., Chacko, S.K. Yallampalli, U., and C. Yallampalli. Novel Lean Type 2 Diabetic Rat Model Using Gestational Low Protein Programming. American Journal of Obstetrics & Gynecology, 214(4), pp 540.e1-e7, 2016.
Quick A.P., Landstrom A.P., Wang Q., Beavers D.L., Reynolds J.O., Barreto-Torres G., Tran V., Showell J., Philippen L.E., Morris S.A., Skapura D., Bos J.M., Pedersen SE, Pautler RG, Ackerman MJ, Wehrens XH. Novel junctophilin-2 mutation A405S is associated with basal septal hypertrophy and diastolic dysfunction. JACC Basic Transl Sci., Feb;2(1): pp56-67, 2017. doi: 10.1016/j.jacbts.2016.11.004. (PMID: 28393127)
Cao Z., Balasubramanian A., Pedersen S.E., Romero J., Pautler R.G., Marrelli S.P. TRPV1-mediated Pharmacological Hypothermia Promotes Improved Functional Recovery Following Ischemic Stroke. Scientific Reports, Dec 15;7(1):17685, 2017. doi: 10.1038/s41598-017-17548-y. (PMID: 29247238).
Sahnoune I., Inoue T., Kesler S.R., Rodgers S.P., Sabek O.M., Pedersen S.E., Zawaski J.A., Nelson K.H., Ris M.D., Leasure J.L., Gaber M.W. Exercise Ameliorates Neurocognitive Impairments in a Translational Model of Pediatric Radiotherapy. Neuro-oncology, Apr 9(5): pp695-704, 2018. doi:10.1093/neuonc/nox197. (PMID: 29121259)